Chemical Alterations – Peripheral Brain-derived Neurotrophic Factor
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چکیده
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that regulates neuronal survival and growth during development. Effects of BDNF on neuronal transmission in the hippocampus, cortex, cerebellum and basal forebrain are important for learning and memory processes [1]. Reduced BDNF may affect synaptic efficiency and connectivity in schizophrenia that is hypothesized to underpin signs and symptoms of the disorder. Due to the difficulty measuring brain levels of BDNF in living people, most studies in this summary have measured levels of BDNF in the periphery (i.e. from blood serum samples).
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